What is ALP?
ALP is an enzyme found throughout the body, mostly in the liver, kidneys and digestive system. It is used for the analysis of liver and gallbladder problems. An ALP test is used to help detect liver disease or bone disorders. Damaged liver cells release ALP into the blood In conditions affecting the liver.
ALP results are considered alongside the results of other tests. Some causes of elevated ALP are liver damage, increased bone cell activity, pregnancy, healing fractures and the use of certain medications. High values on other tests like bilirubin, AST (aspartate aminotransferase), GGT (Gamma Glutamyl transferase), 5'-nucleotidase or ALT (alanine aminotransferase) may confirm liver dysfunction. If GGT or 5'-nucleotidase is normal, especially if calcium and phosphorus markers are abnormal, then the high ALP could be caused by a bone condition.
Why test ALP?
Testing alkaline phosphatase (ALP) is important for several reasons. It helps discover risk factors for lifestyle diseases in time to take action. Knowing your ALP levels can reveal how your liver health is affected by alcohol consumption, weight, virus exposure, or other lifestyle factors. Additionally, it allows you to monitor changes in your blood values as you make lifestyle changes, take supplements, or undergo treatments, ensuring that your liver stays healthy.
What causes low ALP?
Low ALP can be caused by zinc deficiency, malnutrition, magnesium deficiency, protein deficiency, blood transfusions, heart bypass surgery and oral contraceptives. Children and adolescents tend to have higher levels because of bone growth.
Symptoms of low ALP
Low alkaline phosphatase (ALP) can be linked to various health conditions and may cause symptoms such as persistent fatigue, bone pain or fractures, muscle weakness, joint pain, and growth issues in children. If you experience these symptoms, consult a doctor for proper diagnosis and treatment.
What causes high ALP?
High ALP usually signifies either liver damage or increased bone cell activity. High values on other tests like bilirubin, AST (aspartate aminotransferase), GGT (Gamma Glutamyl transferase), 5'-nucleotidase or ALT (alanine aminotransferase) often confirm liver involvement. If GGT or 5'-nucleotidase is normal, especially if calcium and phosphorus markers are abnormal, then the high ALP is probably caused by a bone condition.
Moderately elevated ALP may result from other health conditions.
Symptoms of high ALP
High alkaline phosphatase (ALP) can indicate liver or bone problems. Symptoms include jaundice (yellowing of the skin and eyes), fatigue, abdominal pain, nausea, and unexplained weight loss. Additionally, you might experience bone pain or tenderness, which could signal bone disease. If you notice these symptoms, it's important to consult a doctor for further evaluation and treatment.
Preparations for your blood test
It may be best to avoid fatty foods and alcohol the day before the test.
On the day of the test
Take ID with you when going to take a test. Arrive early and sit quietly for 15 minutes prior to the test the test is taken.